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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
4.55
Human Site:
S435
Identified Species:
10
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S435
L
V
K
T
S
L
F
S
S
K
L
S
T
P
D
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S537
L
V
K
T
S
L
F
S
S
K
L
S
T
P
D
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
H299
K
I
Y
A
T
E
A
H
V
F
P
V
Q
P
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
K436
K
T
S
L
F
S
P
K
L
S
T
P
N
V
S
Rat
Rattus norvegicus
Q6AXN4
673
75694
K436
K
T
S
L
F
S
P
K
L
S
T
P
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
L198
P
Q
Q
V
L
H
S
L
A
H
A
A
M
G
V
Chicken
Gallus gallus
XP_001235442
684
77153
P446
L
A
K
S
S
L
M
P
L
K
A
S
P
G
S
Frog
Xenopus laevis
Q6AX31
660
74320
L429
S
L
L
K
T
A
S
L
K
S
S
L
D
I
G
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
M432
F
K
S
S
V
G
G
M
H
S
S
L
T
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
R347
G
N
R
P
A
S
W
R
S
L
C
D
Q
C
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
P524
R
Y
F
V
D
P
F
P
E
A
D
N
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
0
0
N.A.
0
40
0
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
0
0
N.A.
20
46.6
13.3
13.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
10
10
0
10
10
19
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
10
10
19
0
19
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
10
0
19
0
28
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
10
0
0
0
0
0
0
28
10
% G
% His:
0
0
0
0
0
10
0
10
10
10
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
28
10
28
10
0
0
0
19
10
28
0
0
0
0
0
% K
% Leu:
28
10
10
19
10
28
0
19
28
10
19
19
0
10
19
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
0
10
0
10
19
19
0
0
10
19
10
28
19
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
0
19
0
0
% Q
% Arg:
10
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
10
0
28
19
28
28
19
19
28
37
19
28
0
0
28
% S
% Thr:
0
19
0
19
19
0
0
0
0
0
19
0
28
0
0
% T
% Val:
0
19
0
19
10
0
0
0
10
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _